Tolyporphins J and K, two further porphinoid metabolites from the cyanobacterium Tolypothrix nodosa.

@article{Prinsep1998TolyporphinsJA,
  title={Tolyporphins J and K, two further porphinoid metabolites from the cyanobacterium Tolypothrix nodosa.},
  author={Mich{\`e}le R Prinsep and G. L. Patterson and Linda K. Larsen and Charles D. Smith},
  journal={Journal of natural products},
  year={1998},
  volume={61 9},
  pages={1133-6}
}
Two new porphinoids, tolyporphins J (1) and K (2), have been isolated from the terrestrial cyanobacterium, Tolypothrix nodosa (HT-58-2) and identified by NMR and mass spectral analysis. The activities of tolyporphins J and K in cell sensitization and drug accumulation assays for multidrug resistance (MDR) reversal were compared with those of tolyporphin A. Unusual NMR spectroscopic shifts were observed for tolyporphin J (1) in CDCl3.