Tolmetin and salicylate therapy in acute rheumatic fever: Comparison of clinical efficacy and side-effects.

@article{Karademir2003TolmetinAS,
  title={Tolmetin and salicylate therapy in acute rheumatic fever: Comparison of clinical efficacy and side-effects.},
  author={Selmin Karademir and Deniz A Oguz and Filiz Şenocak and Burhan Ocal and Cemşit Karakurt and Feryal Çabuk},
  journal={Pediatrics international : official journal of the Japan Pediatric Society},
  year={2003},
  volume={45 6},
  pages={
          676-9
        }
}
BACKGROUND The arthritis of rheumatic fever is very responsive to treatment with salicylates, but there are many adverse reactions, especially hepatotoxicity, due to aspirin (acetylsalicylic acid) therapy. These side-effects change the course and duration of rheumatic fever. Other non-steroidal anti-inflammatory drugs may be equally effective, although no reports are available. METHODS We studied 72 patients with rheumatic fever who were admitted to Dr Sami Ulus Children's Hospital between… CONTINUE READING
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