Tolmetin Sodium, a New Anti‐Arthritis Drug: Double‐Blind and Long‐Term Studies

  title={Tolmetin Sodium, a New Anti‐Arthritis Drug: Double‐Blind and Long‐Term Studies},
  author={L. Cordrey},
  journal={Journal of the American Geriatrics Society},
  • L. Cordrey
  • Published 1976
  • Medicine
  • Journal of the American Geriatrics Society
ABSTRACT: The effectiveness of tolmetin sodium in the treatment of rheumatoid arthritis was evaluated by: 1) a 12‐week, double‐blind study with a dosage range of 800–1600 mg daily; and 2) an open 2‐year study with a dosage range of 400–2400 mg daily. The double‐blind study involved 14 patients (7 tolmetin sodium, 7 placebo), and the long‐term study involved 24 patients. At frequent intervals, evaluations were made of joint pain, swelling, stiffness and inflammation; grip strength; walking time… Expand
13 Citations
Clinical Use of Tolmetin Sodium in Patients with Ankylosing Spondylitis: A Review
  • A. Calin
  • Medicine
  • Journal of clinical pharmacology
  • 1983
  • 7
Meta-analysis of dyspepsia and nonsteroidal antiinflammatory drugs.
  • 82
Do NSAIDs cause dyspepsia? a meta-analysis evaluating alternative dyspepsia definitions
  • 66
Sports activities and their effects on high density lipoprotein cholesterol and coronary heart disease.
  • K. Francis
  • Medicine
  • The Journal of orthopaedic and sports physical therapy
  • 1979
N-Pyrrylarylsulfones with High Therapeutic Potential
  • 4
  • PDF


Results of a One‐Year Trial of Tolmetin in Patients with Rheumatoid Arthritis
  • 12
Pharmacologic evaluation of tolectin (tolmetin, mcn-2559) and mcn-2891, two anti-inflammatory agents.
  • 46
Indomethacin--its rightful place in treatment.
  • C. Smyth
  • Medicine
  • Annals of internal medicine
  • 1970
  • 18
Tolmetin versus aspirin in the treatment of rheumatoid arthritis: a controlled double-blind study (Abstract Proc. 6th Pan-American Congress on Rheumatic Diseases, Toronto)
  • J Rheumatol
  • 1974
Tolmetin versus placebo for the treatment of rheumatoid arthritis: a sequential double-blind clinical trial.
  • 20
Pharmacologic evaluation of TolectinB (tolmetin, McN-2559) and McN2891, two anti-inflammatory agents
  • J Pharmacol Exp Therap
  • 1973
The effects of Tolectin in rheumatoid arthritis. (Presented at the 13th International Congress of Rheumatology, Kyoto, Japan, 1973
  • Excerpta Medica Foundation, International Congress Series No
  • 1973
Salicylate therapy for rheumatoid arthritis, in Arthritis and Allied Conditions, ed
  • Lea and Febiger,
  • 1972
Evaluation of the endocrine system response to tolmetin in patients with acute flares of rheumatoid arthritis
  • Tolmetin: A New Non-steroid Anti-inflammatory Agent (Proceedings of a Symposium