Tolmetin: A Review of its Pharmacological Properties and Therapeutic Efficacy in Rheumatic Diseases

@article{Brogden2012TolmetinAR,
  title={Tolmetin: A Review of its Pharmacological Properties and Therapeutic Efficacy in Rheumatic Diseases},
  author={R. Brogden and R. Heel and T. Speight and G. S. Avery},
  journal={Drugs},
  year={2012},
  volume={15},
  pages={429-450}
}
  • R. Brogden, R. Heel, +1 author G. S. Avery
  • Published 2012
  • Medicine
  • Drugs
  • SummarySynopsis: Synopsis: Tolmetin1 (1-methyl-5-p-toluoylpyrrole-2-acetic acid) is a new non-steroidal anti-inflammatory, antipyretic and analgesic agent advocated for use in rheumatoid arthritis, juvenile rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis.Published data suggest that in rheumatoid arthritis, tolmetin 1200 to 1600mg daily is comparable in effectiveness with about one-eighth its dose of indomethacin and with moderate to high doses of aspirin (4 to 4.5g… CONTINUE READING
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    Clinical Pharmacokinetics of Ibuprofen
    • 202

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 174 REFERENCES
    Ocular side-effects of Ibuprofen.
    • 43
    • PDF