Toll-like receptors 2 and 4 gene polymorphisms in a southeastern Chinese population with tuberculosis.

Abstract

Polymorphisms of the toll-like receptor 2 (TLR2) gene (Arg677Trp, Arg753Gln) and the TLR4 gene (Asp299Gly, Thr399Ile) were investigated in 205 tuberculosis (TB) patients and 203 controls. Genetic variations were analysed by DNA sequencing. We revealed that these polymorphisms were rare in the southeastern Chinese population and were not associated with susceptibility to TB.

DOI: 10.1111/j.1744-313X.2009.00892.x

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@article{Xue2010TolllikeR2, title={Toll-like receptors 2 and 4 gene polymorphisms in a southeastern Chinese population with tuberculosis.}, author={Y Q Xue and Z H Q Zhao and H J Wang and L M Jin and Chih-pin Liu and Yanping Wang and Ji-cheng Li}, journal={International journal of immunogenetics}, year={2010}, volume={37 2}, pages={135-8} }