Toll-like receptor mRNA levels in alveolar macrophages after inhalation of endotoxin

@article{Maris2006TolllikeRM,
  title={Toll-like receptor mRNA levels in alveolar macrophages after inhalation of endotoxin},
  author={N. Maris and M. Dessing and A. D. de Vos and P. Bresser and J. S. van der Zee and H. Jansen and C. Spek and T. van der Poll},
  journal={European Respiratory Journal},
  year={2006},
  volume={28},
  pages={622 - 626}
}
Toll-like receptors (TLRs) are pattern-recognition receptors that have been implicated in the initiation of innate immune responses upon the first encounter with invading pathogens. The airways are frequently exposed to various types of lipopolysaccharide (LPS) from the environment or from pathogens. The current study was designed to determine the effect of LPS on TLR gene expression in human alveolar macrophages in vivo. In total, 16 healthy subjects were enrolled in a single-blinded, placebo… Expand
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