Toll-like receptor and innate cytokine responses induced by lactobacilli colonization and human rotavirus infection in gnotobiotic pigs.

@article{Wen2009TolllikeRA,
  title={Toll-like receptor and innate cytokine responses induced by lactobacilli colonization and human rotavirus infection in gnotobiotic pigs.},
  author={Ke Wen and Marli S P Azevedo and Ana Maria Gonzalez and Wei Zhang and Linda J. Saif and Guohua Li and Ahmed Yousef and Lijuan Yuan},
  journal={Veterinary immunology and immunopathology},
  year={2009},
  volume={127 3-4},
  pages={304-15}
}
Toll-like receptors (TLR) play an important role in the recognition of microbes by host sentinel cells that leads to the subsequent innate and adaptive immune responses. In this study, we evaluated the patterns of TLR2-, TLR3- and TLR9-expressing antigen presenting cells (APCs) in spleen and blood of gnotobiotic (Gn) pigs after colonization with a mixture of two strains of lactic acid bacteria (LAB), Lactobacillus acidophilus and Lactobacillus reuteri or infection with the virulent human… CONTINUE READING

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