Toll-like receptor- and filarial antigen-mediated, mitogen-activated protein kinase- and NF-κB-dependent regulation of angiogenic growth factors in filarial lymphatic pathology.

@article{Babu2012TolllikeRA,
  title={Toll-like receptor- and filarial antigen-mediated, mitogen-activated protein kinase- and NF-κB-dependent regulation of angiogenic growth factors in filarial lymphatic pathology.},
  author={Subash Babu and Rajamanickam Anuradha and Nathella P Kumar and Parakkal Jovvian George and Vasanthapuram Kumaraswami and Thomas B Nutman},
  journal={Infection and immunity},
  year={2012},
  volume={80 7},
  pages={2509-18}
}
Filarial lymphatic pathology is of multifactorial origin, with inflammation, lymphangiogenesis, and innate immune responses all playing important roles. The role of Toll-like receptors (TLRs) in the development of filarial pathology is well characterized. Similarly, the association of pathology with elevated levels of plasma angiogenic factors has also been documented. To examine the association between TLR function and the development of lymphangiogenesis in filarial infections, we examined… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 27 references

VEGFs and receptors involved in angiogenesis versus lymphangiogenesis.

Current opinion in cell biology • 2009
View 4 Excerpts
Highly Influenced

Filariasis and lymphoedema

View 4 Excerpts
Highly Influenced

Elevated levels of plasma angiogenic factors are associated with human lymphatic filarial infections

S Bennuru, TB Nutman
Am . J . Trop . Med . Hyg . • 2009

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