Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation.

@article{Omiya2016TolllikeR9,
  title={Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation.},
  author={Shigemiki Omiya and Yosuke Omori and Manabu Taneike and Andrea Protti and Osamu Yamaguchi and Shizuo Akira and Ajay M. Shah and Kazuhiko Nishida and Kinya Otsu},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2016},
  volume={311 6},
  pages={H1485-H1497}
}
We have reported that the Toll-like receptor 9 (TLR9) signaling pathway plays an important role in the development of pressure overload-induced inflammatory responses and heart failure. However, its role in cardiac remodeling after myocardial infarction has not been elucidated. TLR9-deficient and control C57Bl/6 wild-type mice were subjected to left… CONTINUE READING