Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis

Abstract

Toll-like receptors (TLRs) are a family of transmembrane pattern recognition receptors (PRR) that play a key role in innate and adaptive immunity by recognizing structural components unique to bacteria, fungi and viruses. TLR4 is the most studied of the TLRs, and its primary exogenous ligand is lipopolysaccharide, a component of Gram-negative bacterial… (More)
DOI: 10.1186/1755-1536-3-21

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