Toll-like receptor 4 plays an anti-HBV role in a murine model of acute hepatitis B virus expression.

Abstract

AIM Toll-like receptor 4 (TLR4) has been shown to be important for bacterial infection, especially to lipopolysaccharide signaling. Its possible role in HBV infection is studied in the present study. MATERIALS AND METHODS pHBV3.6 plasmid, containing full-length HBV genome was used in the murine model of acute HBV expression by hydrodynamics in vivo… (More)

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