Toll-like receptor 4: innate immune regulator of neuroimmune and neuroendocrine interactions in stress and major depressive disorder

@inproceedings{Liu2014TolllikeR4,
  title={Toll-like receptor 4: innate immune regulator of neuroimmune and neuroendocrine interactions in stress and major depressive disorder},
  author={Jiajun Liu and Femke T A Buisman-Pijlman and Mark R Hutchinson},
  booktitle={Front. Neurosci.},
  year={2014}
}
Major depressive disorder (MDD) poses one of the highest disease burdens worldwide. Yet, current treatments targeting serotonergic and noradrenaline reuptake systems are insufficient to provide long-term relief from depressive symptoms in most patients, indicating the need for new treatment targets. Having the ability to influence behavior similar to depressive symptoms, as well as communicate with neuronal and neuroendocrine systems, the innate immune system is a strong candidate for MDD… CONTINUE READING
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Citation: Liu J, Buisman-Pijlman F and Hutchinson MR (2014) Toll-like receptor 4: innate immune regulator of neuroimmune and neuroendocrine interactions in stress and major depressive disorder

  • September
  • Front. Neurosci. 8:309. doi: 10.3389/fnins.2014…
  • 2014
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