Toll-like receptor 3 signaling induces apoptosis in human head and neck cancer via survivin associated pathway.

  title={Toll-like receptor 3 signaling induces apoptosis in human head and neck cancer via survivin associated pathway.},
  author={Nozomi Nomi and Satoru Kodama and Masashi Suzuki},
  journal={Oncology reports},
  volume={24 1},
The innate immune system builds up host defense against a huge diversity of pathogens, such as viruses, bacteria and fungi. Toll-like receptors (TLRs) are one of the pattern recognition receptors that trigger the initiation of various defense mechanisms. The expression of TLRs represents an important link between innate and adaptive immune responses. The expression of TLRs in several cancer cell types has been reported; however, the exact roles they play in cancers are still unclear. In this… CONTINUE READING


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