Toll-like receptor 3 signaling induces apoptosis in human head and neck cancer via survivin associated pathway.

@article{Nomi2010TolllikeR3,
  title={Toll-like receptor 3 signaling induces apoptosis in human head and neck cancer via survivin associated pathway.},
  author={Nozomi Nomi and Satoru Kodama and Masashi Suzuki},
  journal={Oncology reports},
  year={2010},
  volume={24 1},
  pages={225-31}
}
The innate immune system builds up host defense against a huge diversity of pathogens, such as viruses, bacteria and fungi. Toll-like receptors (TLRs) are one of the pattern recognition receptors that trigger the initiation of various defense mechanisms. The expression of TLRs represents an important link between innate and adaptive immune responses. The expression of TLRs in several cancer cell types has been reported; however, the exact roles they play in cancers are still unclear. In this… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 29 references

Induction of cMycdependent cell proliferation through toll - like receptor 3 in head and neck cancer

  • JF He, WH Jia, +4 authors YX Zeng
  • Int J Mol Med
  • 2008

Poly I : C enhances cycloheximideinduced apoptosis of tumor cells through TLR 3 pathway

  • E Khavalevsky, L Rivkin, J Rashmilewitz, E Galun, H Giladi
  • BMC Cancer
  • 2008

through a PKCalphadependent mechanism

  • Q Jiang, H Wei, Z Tian
  • Carcinogenesis
  • 2008

Genetic polymorphisms of TLR 3 are associated with nasophryngeal carcinoma risk in Cantonese population

  • W He, Li Qu, L Wang, W Chen, N Li, X Cao
  • BMC Cancer
  • 2007

Toll - like receptor 3 expressed by melanoma cells as a target for therapy ?

  • B Alaun, S Lebecque, S Matikainen, D Rimoldi, P Romero
  • Clin Cancer Res
  • 2007

and is involved in the development of human pancreatic duct cell tumors

  • WJ Kaiser, JL Kaufman, MK Offermann
  • Cancer
  • 2007

Similar Papers

Loading similar papers…