Toll-like receptor 3 polymorphism rs3775291 is not associated with choroidal neovascularization or polypoidal choroidal vasculopathy in Chinese subjects.

@article{Sng2011TolllikeR3,
  title={Toll-like receptor 3 polymorphism rs3775291 is not associated with choroidal neovascularization or polypoidal choroidal vasculopathy in Chinese subjects.},
  author={Chelvin C A Sng and Peter D Cackett and Ian Yeo and Anbupalam Thalamuthu and Anandalakshmi Venkatraman and Divya Venkataraman and Adrian H. C. Koh and E. Shyong Tai and Tien Yin Wong and Tin Aung and Eranga Vithana},
  journal={Ophthalmic research},
  year={2011},
  volume={45 4},
  pages={191-6}
}
BACKGROUND/AIMS Age-related macular degeneration (AMD) is a leading cause of visual impairment. A single-nucleotide polymorphism (SNP; rs3775291) in the Toll-like receptor 3 (TLR3) gene has recently been implicated in the pathogenesis of AMD in Caucasian populations. The aim of this study was to examine this association in Chinese persons with choroidal neovascularization (CNV) secondary to AMD and polypoidal choroidal vasculopathy (PCV). METHODS This was an observational cross-sectional… CONTINUE READING