Toll-like receptor 2 (TLR2) mediates intracellular signalling in human keratinocytes in response to Malassezia furfur

@article{Baroni2005TolllikeR2,
  title={Toll-like receptor 2 (TLR2) mediates intracellular signalling in human keratinocytes in response to Malassezia furfur},
  author={Adone Baroni and Manuela Orlando and Giovanna Donnarumma and Pietro Farro and Maria Rosaria Iovene and Maria Antonietta Tufano and Elisabetta Buommino},
  journal={Archives of Dermatological Research},
  year={2005},
  volume={297},
  pages={280-288}
}
Toll-like receptors (TLRs) are crucial players in the innate immune response to microbial invaders. The lipophilic yeast Malassezia furfur has been implicated in the triggering of scalp lesions in psoriasis. The aim of the present study was to assess the role of TLRs in the defence against M. furfur infection. The expression of the myeloid differentiation factor 88 (MyD88) gene, which is involved in the signalling pathway of many TLRs, was also analysed. In addition, a possible correlation of… CONTINUE READING
Highly Cited
This paper has 64 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

β-Defensins: Work in Progress.

Advances in experimental medicine and biology • 2016
View 2 Excerpts

The Role of Malassezia spp. in Atopic Dermatitis

Journal of clinical medicine • 2015
View 1 Excerpt

65 Citations

051015'09'12'15'18
Citations per Year
Semantic Scholar estimates that this publication has 65 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 50 references

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors.

Proceedings of the National Academy of Sciences of the United States of America • 2000
View 3 Excerpts
Highly Influenced

Differential role of Myd88 in macrophage-mediated responses to opportunistic fungal pathogens

KA Marr, SA Balajee, +5 authors WC Liles
Infect Immun • 2003
View 2 Excerpts