Toll- and NOD-like receptor mRNA expression in canine sino-nasal aspergillosis and idiopathic lymphoplasmacytic rhinitis.

@article{Mercier2012TollAN,
  title={Toll- and NOD-like receptor mRNA expression in canine sino-nasal aspergillosis and idiopathic lymphoplasmacytic rhinitis.},
  author={Elise Mercier and Iain Robertson Peters and Michael Joseph Day and C{\'e}cile M Clercx and Dieter Peeters},
  journal={Veterinary immunology and immunopathology},
  year={2012},
  volume={145 3-4},
  pages={
          618-24
        }
}
The pathogenesis of canine sino-nasal aspergillosis (SNA) and lymphoplasmacytic rhinitis (LPR) remains poorly understood. The innate immune system is implicated in the etiology of human chronic rhinosinusitis. Therefore, we hypothesized that dysfunction in innate immunity could be implicated in the pathogenesis of SNA and LPR. Expression of messenger RNA (mRNA) encoding Toll-like receptors (TLRs) 1-10 and NOD-like receptors (NODs) 1 and 2 in nasal mucosal biopsies from SNA or LPR dogs was… CONTINUE READING
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