Toll-Like Receptor 3 Contributes to Wallerian Degeneration after Peripheral Nerve Injury.

Abstract

OBJECTIVE It is well known that Schwann cells play an important role in Wallerian degeneration after peripheral nerve injury. Previously, we reported that toll-like receptor 3 (TLR3) is expressed on Schwann cells, implicating its role in Schwann cell activation during Wallerian degeneration. In this study, we tested this possibility using TLR3 knock-out… (More)
DOI: 10.1159/000449134

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