Toll-Like Receptor (TLR) and Nucleosome-binding Oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk

@inproceedings{Ashton2010TollLikeR,
  title={Toll-Like Receptor (TLR) and Nucleosome-binding Oligomerization Domain (NOD) gene polymorphisms and endometrial cancer risk},
  author={Katie A. Ashton and Anthony M Proietto and Geoffrey R Otton and Ian M. Symonds and Mark Mcevoy and John R Attia and Rodney J. Scott},
  booktitle={BMC Cancer},
  year={2010}
}
Endometrial cancer is the most common gynaecological malignancy in women of developed countries. Many risk factors implicated in endometrial cancer trigger inflammatory events; therefore, alterations in immune response may predispose an individual to disease. Toll-like receptors (TLRs) and nucleosome-binding oligomerization domain (NOD) genes are integral to the recognition of pathogens and are highly polymorphic. For these reasons, the aim of the study was to assess the frequency of… CONTINUE READING