Tolerogenic effects of interferon-gamma with induction of allergen-specific interleukin-10-producing regulatory B cell (Br1) changes in non-IgE-mediated food allergy.

@article{Noh2012TolerogenicEO,
  title={Tolerogenic effects of interferon-gamma with induction of allergen-specific interleukin-10-producing regulatory B cell (Br1) changes in non-IgE-mediated food allergy.},
  author={Joonyong Noh and Geunwoong Noh and Soo Jin Lee and Jae Ho Lee and Aram Kim and Hyuk Soon Kim and Wahn Soo Choi},
  journal={Cellular immunology},
  year={2012},
  volume={273 2},
  pages={140-9}
}
In this study, specific oral tolerance induction using interferon-gamma (IFN-γ) could successfully treat food allergies. Allergen-specific IL-10-producing regulatory B cell (Br1) responses are characteristic in immune tolerance of food allergies. The in-vivo effects of IFN-γ on allergen-induced changes in Br1 proportion and numbers in food allergies were… CONTINUE READING