Tolerogenic dendritic cells in experimental autoimmune encephalomyelitis, specific tolerance induction?

Abstract

Background Specific cell therapy with tolerogenic Dendritic Cells (tolDCs) loaded with autoantigens is a promising tool for the attenuation of pathogenic T cells in autoimmune diseases such as Multiple Sclerosis (MS). The aim of this study was to analyse the in vitro effect of tolerogenic bone marrow derived DCs (BM-DCs) loaded with Myelin Oligodendrocyte Glycoprotein (MOG) 40-55 peptide from C57BL/6 mice, on the specific proliferation of splenocytes of mice with EAE.

DOI: 10.1186/1479-5876-10-S3-P27

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Cite this paper

@inproceedings{SellsMoreno2012TolerogenicDC, title={Tolerogenic dendritic cells in experimental autoimmune encephalomyelitis, specific tolerance induction?}, author={Carla Sell{\'e}s-Moreno and Cristina Ramo-Tello and Laia Grau-L{\'o}pez and Ricardo Pujol-Borrel and Eva M Mart{\'i}nez-C{\'a}ceres}, booktitle={Journal of Translational Medicine}, year={2012} }