Tolerogenic dendritic cells and the quest for transplant tolerance

Abstract

In recent years, there has been a shift from the perception of dendritic cells (DCs) solely as inducers of immune reactivity to the view that these cells are crucial regulators of immunity, which includes their ability to induce and maintain tolerance. Advances in our understanding of the phenotypical and functional plasticity of DCs, and in our ability to… (More)
DOI: 10.1038/nri2132

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