Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barré syndrome.

Abstract

Guillain-Barré syndrome following Campylobacter jejuni infection is frequently associated with anti-ganglioside autoantibodies mediated by molecular mimicry with ganglioside-like oligosaccharides on bacterial lipopolysaccharide (LPS). The regulation of antibody responses to these T-cell-independent antigens is poorly understood, and only a minority of… (More)

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@article{Bowes2002ToleranceTS, title={Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barr{\'e} syndrome.}, author={Tyrone Bowes and Eric R. Wagner and Judith Boffey and Dawn Nicholl and Lynne E Cochrane and Mustapha Benboubetra and Joe Conner and Koichi Furukawa and Hugh John Willison}, journal={Infection and immunity}, year={2002}, volume={70 9}, pages={5008-18} }