Tolerance to and cross-tolerance among ethanol, pentobarbital and chlordiazepoxide.


The acute administration of ethanol, pentobarbital and chlordiazepoxide impaired, in a dose-dependent manner, the performance of rats on the moving-belt and two-way shuttle-box avoidance tests. Administration of these drugs for three weeks resulted in tolerance to their motor-impairing effects. Tolerance to ethanol or pentobarbital was characterized by a… (More)


  • Presentations referencing similar topics