Tolerance to Oxidative Stress in Budding Yeast by Heterologous Expression of Catalases A and T from Debaryomyces hansenii.

@article{Gonzlez2020ToleranceTO,
  title={Tolerance to Oxidative Stress in Budding Yeast by Heterologous Expression of Catalases A and T from Debaryomyces hansenii.},
  author={James Gonz{\'a}lez and Rom{\'a}n Castillo and Miguel Angel Garcia-Campos and Diego Noriega-Samaniego and Viviana Escobar-S{\'a}nchez and Lucero Romero-Aguilar and Luisa Alba-Lois and Claudia Segal-Kischinevzky},
  journal={Current microbiology},
  year={2020}
}
The function of catalases A and T from the budding yeast Saccharomyces cerevisiae (ScCta1 and ScCtt1) is to decompose hydrogen peroxide (H2O2) to mitigate oxidative stress. Catalase orthologs are widely found in yeast, suggesting that scavenging H2O2 is crucial to avoid the oxidative damage caused by reactive oxygen species (ROS). However, the function of catalase orthologs has not yet been experimentally characterized in vivo. Here, we heterologously expressed Debaryomyces hansenii DhCTA1 and… 
2 Citations
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