Tolerance susceptibility of newly generating memory B cells.

  title={Tolerance susceptibility of newly generating memory B cells.},
  author={Phyllis Jean Linton and A Rudie and Norman R. Klinman},
  journal={Journal of immunology},
  volume={146 12},
Newly generating memory B cells rapidly accumulate somatic mutations that can alter their Ag-combining sites and potentially engender recognition of self determinants. To investigate the possibility that, during their emergence secondary B cells pass through a window of tolerance susceptibility, we have examined the in vitro generation of memory B cells in… CONTINUE READING