Tolerance of simulated amniotic fluid in premature neonates.

@article{Sullivan2002ToleranceOS,
  title={Tolerance of simulated amniotic fluid in premature neonates.},
  author={Sandra E. Sullivan and Darlene A. Calhoun and Akhil Maheshwari and Terri Ashmeade and David A. Nash Auerbach and Mark L Hudak and Susan E Beltz and Robert D. M.D Christensen},
  journal={The Annals of pharmacotherapy},
  year={2002},
  volume={36 10},
  pages={
          1518-24
        }
}
OBJECTIVE To assess the tolerance of simulated amniotic fluid enterally administered in premature neonates. DESIGN A multicentered, Phase I, dose-escalation trial was accomplished among 30 preterm neonates. Groups of 10 patients received 5, 10, or 20 mL/kg/d enterally of the amniotic fluid solution, divided into every-3-hour dosing, for 3 days. MAIN OUTCOME MEASURES Amount and character of emesis, stools, and gastric residuals; changes in abdominal girth; presence of a skin rash; blood… CONTINUE READING
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