Tolerance of dormant and active cells in Pseudomonas aeruginosa PA01 biofilm to antimicrobial agents.

  title={Tolerance of dormant and active cells in Pseudomonas aeruginosa PA01 biofilm to antimicrobial agents.},
  author={Jaeeun Kim and Ji-Sook Hahn and Michael J. Franklin and Philip S Stewart and Jeyong Yoon},
  journal={The Journal of antimicrobial chemotherapy},
  volume={63 1},
OBJECTIVES The aim of the study was to determine the susceptibility of active and dormant cell populations from Pseudomonas aeruginosa biofilms to non-antibiotic antimicrobial agents such as chlorine, hydrogen peroxide and silver ions in comparison with antibiotics. METHODS Active cells in colony biofilm were differentially labelled by induction of a green fluorescent protein (GFP). Active and dormant cells were sorted in phosphate buffered solution by flow cytometry. Reductions in viability… CONTINUE READING


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