Tolerance and cross-tolerance among psychotomimetic drugs


A fixed-ratio schedule of milk reinforcement (FR 30) was used to study tolerance to the effects of d-LSD, l-LSD, BOL, psilocybin, mescaline, and d-amphetamine in the rat. A decrease in the amount of disruption of bar-pressing occurs with repeated daily administration of appropriate doses of all of the “psychotomimetic” compounds, and cross-tolerance was… (More)
DOI: 10.1007/BF00401404


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@article{Appel1968ToleranceAC, title={Tolerance and cross-tolerance among psychotomimetic drugs}, author={J. B. Appel and Doris Freedman}, journal={Psychopharmacologia}, year={1968}, volume={13}, pages={267-274} }