Tolerability of Paracetamol

@article{Graham2005TolerabilityOP,
  title={Tolerability of Paracetamol},
  author={Garry G Graham and Kieran F Scott and Richard O Day},
  journal={Drug Safety},
  year={2005},
  volume={28},
  pages={227-240}
}
AbstracThe excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported after therapeutic doses, but critical analysis indicates that most patients with alleged toxicity from therapeutic doses have taken overdoses. Importantly, prospective studies indicate that therapeutic doses of paracetamol are an unlikely… Expand
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