Tolerability and safety of rituximab (MabThera).

  title={Tolerability and safety of rituximab (MabThera).},
  author={Eva K Kimby},
  journal={Cancer treatment reviews},
  volume={31 6},
Rituximab, a human/mouse chimeric anti-CD20 antibody, has become part of standard therapy for patients with CD20-expressing B-cell lymphoma, and is currently under investigation for other indications including autoimmune diseases, in particular rheumatoid arthritis (RA). Its characteristic tolerability profile was established soon after clinical testing began and compares favourably with chemotherapy. The majority of patients experience mild to moderate infusion-related reactions (IRRs) during… CONTINUE READING
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