Tolerability and safety of HIV protease inhibitors in adults.

  title={Tolerability and safety of HIV protease inhibitors in adults.},
  author={Paul Edward Sax and Princy N.S. Kumar},
  journal={Journal of acquired immune deficiency syndromes},
  volume={37 1},
Antiretroviral drugs are associated with both short-term and long-term adverse events. Like other HIV drugs, protease inhibitors (PIs) may affect metabolic processes influencing body shape and body tissue composition, appearance, bone integrity, and cardiovascular status. However, numerous confounding variables including age, cigarette smoking, body mass index (BMI), duration of HIV infection, degree of immunodeficiency, concomitant antiretroviral agents, extent of previous treatment, and… CONTINUE READING