Tolerability and safety aspects of mirtazapine

@article{Nutt2002TolerabilityAS,
  title={Tolerability and safety aspects of mirtazapine},
  author={D. Nutt},
  journal={Human Psychopharmacology: Clinical and Experimental},
  year={2002},
  volume={17}
}
  • D. Nutt
  • Published 2002
  • Medicine
  • Human Psychopharmacology: Clinical and Experimental
The tolerability and safety profile of the noradrenergic and specific serotonergic antidepressant (NaSSA) mirtazapine reflects its unique pharmacological profile. The 5‐HT2 blocking effect contributes towards its anxiolytic effects and benefits on sleep, as well as preventing the sexual dysfunction that may occur with non‐specific stimulation of the serotonin system by drugs such as the selective serotonin reuptake inhibitors (SSRIs). In addition, 5‐HT3 blockade by mirtazapine helps to prevent… Expand
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