Toehold-mediated nonenzymatic amplification circuit on graphene oxide fluorescence switching platform for sensitive and homogeneous microRNA detection.

@article{Huang2015ToeholdmediatedNA,
  title={Toehold-mediated nonenzymatic amplification circuit on graphene oxide fluorescence switching platform for sensitive and homogeneous microRNA detection.},
  author={R. C. Huang and Yuhui Liao and Xiaoming Zhou and Da Xing},
  journal={Analytica chimica acta},
  year={2015},
  volume={888},
  pages={162-72}
}
A novel graphene oxide (GO) fluorescence switch-based homogenous system has been developed to solve two problems that are commonly encountered in conventional GO-based biosensors. First, with the assistance of toehold-mediated nonenzymatic amplification (TMNA), the sensitivity of this system greatly surpasses that of previously described GO-based biosensors… CONTINUE READING