Tocotrienol offers better protection than tocopherol from free radical-induced damage of rat bone.

@article{Ahmad2005TocotrienolOB,
  title={Tocotrienol offers better protection than tocopherol from free radical-induced damage of rat bone.},
  author={Naveed Ahmad and Bin Abdul Kadir Khalid and Douglas Alwyn Luke and Soelaiman Ima Nirwana},
  journal={Clinical and experimental pharmacology & physiology},
  year={2005},
  volume={32 9},
  pages={761-70}
}
1. Free radicals generated by ferric nitrilotriacetate (FeNTA) can activate osteoclastic activity and this is associated with elevation of the bone resorbing cytokines interleukin (IL)-1 and IL-6. In the present study, we investigated the effects of 2 mg/kg FeNTA (2 mg iron/kg) on the levels of serum IL-1 and IL-6 with or without supplementation with a palm oil tocotrienol mixture or alpha-tocopherol acetate in Wistar rats. 2. The FeNTA was found to elevate levels of IL-1 and IL-6. Only the… CONTINUE READING
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