Tocopherol succinate: a promising radiation countermeasure.

  title={Tocopherol succinate: a promising radiation countermeasure.},
  author={Vijay K Singh and Darren S Brown and T C Kao},
  journal={International immunopharmacology},
  volume={9 12},
Vitamin E is composed of a family of eight isomers known as tocols; consisting of four tocopherols and four tocotrienols that exist in four isomeric forms: alpha (alpha), beta (beta), gamma (gamma), and delta (delta). Earlier we have demonstrated the radioprotective efficacy of the succinate ester of alpha-tocopherol (alpha-tocopherol succinate, TS). CD2F1 mice were injected subcutaneously with 400 mg/kg of TS and irradiated with different doses of 60Co gamma-radiation to determine its… CONTINUE READING