Tocilizumab in rheumatoid arthritis: a meta-analysis of efficacy and selected clinical conundrums.

@article{Navarro2014TocilizumabIR,
  title={Tocilizumab in rheumatoid arthritis: a meta-analysis of efficacy and selected clinical conundrums.},
  author={Geraldine Navarro and Sara Taroumian and Nashla S Barroso and Lewei Duan and Daniel e. Furst},
  journal={Seminars in arthritis and rheumatism},
  year={2014},
  volume={43 4},
  pages={458-69}
}
INTRODUCTION Tocilizumab (TCZ) is a biological agent used for the treatment of moderate to severe rheumatoid arthritis (RA). In the present systematic literature review and meta-analysis, we provide an update on the efficacy and safety of TCZ and our clinical comments for the treatment of RA. METHODS We searched PubMed for randomized, double-blind, placebo-controlled clinical trials investigating the effects of TCZ on RA. The initial search included articles from 1966 to December 2011. The… CONTINUE READING