Tobacco smoking, alcohol drinking, betel quid chewing, and the risk of head and neck cancer in an East Asian population

  title={Tobacco smoking, alcohol drinking, betel quid chewing, and the risk of head and neck cancer in an East Asian population},
  author={Yuan-Chin Amy Lee and Shuang Li and Yuji Chen and Qian Li and Chien-Jen Chen and Wan-Lun Hsu and Pei-Jen Lou and Cairong Zhu and Jian Pan and Hongbing Shen and Hongxia Ma and Lin Cai and Baochang He and Yu Wang and Xiaoyan Zhou and Qing-hai Ji and Baosen Zhou and Wei Wu and Jie Ma and Paolo Boffetta and Zuo-Feng Zhang and Min Dai and Mia Hashibe},
  journal={Head \& Neck},
  pages={102 - 92}
The smoking prevalence among men in China is high, but the head and neck cancer incidence rates are low. This study's purpose was to investigate the impact of tobacco, betel quid, and alcohol on head and neck cancer risk in East Asia. 

Effects of Betel Quid, Smoking and Alcohol on Oral Cancer Risk: A Case–Control Study in Hunan Province, China

There was a positive correlation between betel quid chewing and risk of oral cancer in the Hunan Province and the risk of cancer was significantly elevated at high levels of intake and prolonged duration of consumption of betelQuid, smoking, and alcohol.

Tobacco smoking, chewing habits, alcohol drinking and the risk of head and neck cancer in Nepal

Both high frequency and long duration of these habits were strong risk factors for HNC among the Nepalese with clear dose–response trends and preventive strategies against starting these habits and support for quitting these habits are necessary to decrease the incidence of HNC in Nepal.

Alcohol consumption, tobacco smoking, betel quid chewing and oral health associations with hypopharyngeal cancer among men in Central South China: a case–control study

It is shown for what is believed to be the first time the association of increased hypopharyngeal cancer incidence with alcohol, tobacco, betel quid and oral hygiene in China and alcohol may play a larger role in this population than in populations in other areas.

Alcohol‐related head and neck cancer: Summary of the literature

There is a need to forge collaborations among clinicians, researchers, and social workers, to address the problem of alcohol consumption in the growing population of HNC survivors.

Tobacco use and betel quid chewing among adults in Myanmar- estimates and social determinants from demographic and health survey, 2015–16

In Myanmar, prevalence of both tobacco use and betel quid chewing was high particularly among men, and ‘dual use’ of both smoking and chewing tobacco should also be urgently addressed.

Tobacco, Alcohol and Family History of Cancer as Risk Factors of Oral Squamous Cell Carcinoma: Case-Control Retrospective Study

Alcohol and tobacco may be associated with an increase in the risk of Oral Squamous Cell Carcinoma and risk factors; including tobacco, alcohol and Family History of Cancer.

Epidemiology of head and neck cancers: an update.

To decrease HNC incidence, measures to reduce tobacco use and alcohol consumption remain essential and improvement of HPV vaccination coverage is also a major objective.

Head and neck cancer prevention: from primary prevention to impact of clinicians on reducing burden.

Molecular-based research on HNC tumors holds promise for early stage detection, screening, vaccination, disease follow-up, and progression, with priority toward risk factor prevention and earlier diagnosis.

Oral cancer: Clinicopathological features and associated risk factors in a high risk population presenting to a major tertiary care center in Pakistan

Male patients belonging to low SES in their forties who had chewing habits for years constituted the bulk of OSCC and Buccal mucosa was the most common site in chewers and the majority presented with late stage tumors.

Review of the Literature on Oral Cancer: Epidemiology, Management and Evidence-based Traditional Medicine Treatment

It is thus desirable to scientifically validate phytochemicals in order to integrate alternative medicine as part of national cancer management strategy.



Tobacco, alcohol, body mass index, physical activity, and the risk of head and neck cancer in the prostate, lung, colorectal, and ovarian (PLCO) cohort

Estimation of attributable fractions for tobacco and alcohol, and investigation of the association between body mass index (BMI) and head and neck cancer risk have largely been in case‐control

Tobacco, Alcohol and Dietary Factors Associated with the Risk of Oral Cancer among Japanese

Smoking cessation, drinking control and frequent intake of raw vegetables and fruit among Japanese are likely to be effective preventive measures against oral cancer.

Systematic review with meta‐analysis: race‐specific effects of alcohol and tobacco on the risk of oesophageal squamous cell carcinoma

Oesophageal squamous cell carcinoma (OSCC) is associated with alcohol use, tobacco use and African or Asian descent. However, little is known about how racial background modifies the effects of

Tobacco smoking, alcohol consumption, and risk of oral cancer: a case-control study in Beijing, People's Republic of China

The association with tobacco consumption was strong for squamous cell carcinoma but there was no trend in risk associated with tobacco for adenocarcinomas and other histologic types and the combined effects of tobacco and alcohol appear to be approximately multiplicative in males.

Alcohol drinking, cigarette smoking, and the development of squamous cell carcinoma of the esophagus: epidemiology, clinical findings, and prevention

Effective follow up using endoscopy with Lugol staining or narrow band imaging endoscopes is strongly recommended for high-risk populations, such as smokers, heavy drinkers, people with experience of flushing after the drinking of alcohol, and patients with UADT cancer.

A Comprehensive Analysis on the Association between Tobacco-Free Betel Quid and Risk of Head and Neck Cancer in Taiwanese Men

The results supported the positive association between BQ and HNC and suggested that BQ cessation is effective in reducing HNC risk and should be encouraged.

Effect of dietary antioxidants and risk of oral, pharyngeal and laryngeal squamous cell carcinoma according to smoking and drinking habits

Dietary antioxidant intake prevents head and neck squamous cell carcinoma in smokers and drinkers, and the protective effect of these antioxidants was seen in both men and women.

Alcohol, Tobacco and Genetic Susceptibility in Relation to Cancers of the Upper Aerodigestive Tract in Northern Italy

The present study confirmed the importance of tobacco smoking and alcohol drinking as the main risk factors for upper aerodigestive tract cancers, indicating that about 68% of cancers among populations in northern Italy can be attributed to the combination of these risk factors.

Interaction between Tobacco and Alcohol Use and the Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium

It is confirmed that the joint effect between tobacco and alcohol use is greater than multiplicative on head and neck cancer risk, however, a substantial proportion of head and head cancers cannot be attributed to tobacco or alcohol use, particularly for oral cavity cancer and for head andneck cancer among women and among young-onset cases.

Cigarette smoke inhalation and risk of lung cancer: a case–control study in a large Japanese population

  • K. FukumotoHidemi Ito T. Takezaki
  • Medicine
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation
  • 2015
It was showed that inhalation of cigarette smoke is a significant risk for LC independent from pack-years in a Japanese population, and the OR adjusted for basic confounding factors and pack-year of the risk of LC in the inhalation group was significantly higher than that in the noninhalation group.