Tobacco and Arabidiopsis SLT1 mediate salt tolerance of yeast

  title={Tobacco and Arabidiopsis SLT1 mediate salt tolerance of yeast},
  author={Tracie K. Matsumoto and Jos{\'e} Manuel Pardo and Satomi Takeda and Ray Anthony Bressan and Paul Mike Hasegawa},
  journal={Plant Molecular Biology},
A tobacco cDNA (NtSLT1, for Nicotiana tabacum sodium- and lithium-tolerant) was isolated by functional complementation of the salt-sensitive phenotype of a calcineurin (CaN)-deficient yeast mutant (cnbΔ, regulatory subunit null). CaN is a Ca2+/calmodulin-dependent type 2B protein phosphatase that regulates Na+ homeostasis in yeast. This phosphatase modulates plasma membrane K+/Na+ selectivity through the activation of high-affinity K+ transport, and increaseses extracellular Na+ efflux by… CONTINUE READING
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