To the Editor--Propranolol, a β-adrenoreceptor blocker, prevents arrhythmias also by its sodium channel blocking effect.


Calvillo et al report a ventricular antiarrhythmic effect of high-dose propranolol in a model of long QT syndrome 3 (LQT3). They interpret their findings as support for the therapeutic efficacy of β-adrenoceptor blockers in LQT3. It seems important to put their findings in context: Propranolol is not only a β-adrenoceptor blocker but also a sodium channel… (More)
DOI: 10.1016/j.hrthm.2013.12.027


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