To live or let die – complexity within the E2F1 pathway

  title={To live or let die – complexity within the E2F1 pathway},
  author={A Poppy Roworth and Fatemeh Ghari and Nicholas B. La Thangue},
  booktitle={Molecular & cellular oncology},
The E2F1 transcription factor is a recognized regulator of the cell cycle as well as a potent mediator of DNA damage-induced apoptosis and the checkpoint response. Understanding the diverse and seemingly dichotomous functions of E2F1 activity has been the focus of extensive ongoing research. Although the E2F pathway is frequently deregulated in cancer, the… CONTINUE READING

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Citations per Year

Citation Velocity: 5

Averaging 5 citations per year over the last 3 years.

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