To elute or not to elute in immunocapture bottom-up LC-MS.

Abstract

Immunocapture-based bottom-up LC-MS is a promising technique for the quantification of low abundant proteins. Magnetic immunocapture beads provide efficient enrichment from complex samples through the highly specific interaction between the target protein and its antibody. In this article, we have performed the first thorough comparison between digestion of… (More)
DOI: 10.1016/j.jchromb.2017.03.044

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