To die or not to die, does it change the function? Behavior of transgenic mice reveals a role for developmental cell death
@article{RondiReig2002ToDO, title={To die or not to die, does it change the function? Behavior of transgenic mice reveals a role for developmental cell death}, author={Laure Rondi-Reig and Jean Mariani}, journal={Brain Research Bulletin}, year={2002}, volume={57}, pages={85-91} }
20 Citations
Role of programmed cell death in normal neuronal development and function
- BiologyAnatomical science international
- 2004
Examination of organisms where death genes have been genetically eliminated reveals that programmed cell death may play an important role in sculpting gross brain structure during early development of the neural tube.
Absence of Stress Response in Dorsal Raphe Nucleus in Modulator of Apoptosis 1-Deficient Mice
- Biology, PsychologyMolecular Neurobiology
- 2018
Data suggest that MOAP-1 is required in the regulation of stress response in the dorsal raphe nucleus (DRN) in young wild-type control mice, and Crosstalk between BDNF and 5-HT appears to play an important role in this stress response.
Adaptive roles of programmed cell death during nervous system development.
- BiologyAnnual review of neuroscience
- 2006
The programmed cell death of developing cells is considered an essential adaptive process that evolved to serve diverse roles and perturb (inhibit) PCD is reviewed to determine the possible repercussions for nervous system development and function.
Bcl-2 over-expression fails to prevent age-related loss of calretinin positive neurons in the mouse dentate gyrus
- BiologyMolecular Neurodegeneration
- 2006
Data suggest an age-related loss of CR positive neurons but not total neuronal loss in normal mice and this age- related neuronal change is not prevented by Bcl-2 over-expression.
Behavioral effects of Bcl-2 deficiency: implications for affective disorders.
- Psychology, BiologyPharmacological reports : PR
- 2008
The relationship between Bcl-2 and behavior is explored using mice with a targeted mutation but with a different background strain than previously tested, and the current lack of effect on anxiety measures may be related to high baseline anxiety of WTanimals.
GASTRIC INHIBITORY POLYPEPTIDE IN THE BRAIN
- Biology
- 2009
This investigation investigates differences in adult hippocampal neurogenesis between male and female rats of 2 different strains and demonstrates for the first time the presence of GIP in the brain and provides evidence for a regulatory function of Gip in progenitor cell proliferation.
Dexamethasone induces apoptosis in the developing rat amygdala in an age-, region-, and sex-specific manner
- BiologyNeuroscience
- 2011
NMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell death
- BiologyProceedings of the National Academy of Sciences
- 2006
The results indicate that NMDA receptors play a survival role for somatosensory relay neurons during synaptogenesis by inhibiting Bax-dependent developmental cell death.
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