Tn125-related acquisition of blaNDM-like genes in Acinetobacter baumannii.

@article{Poirel2012Tn125relatedAO,
  title={Tn125-related acquisition of blaNDM-like genes in Acinetobacter baumannii.},
  author={Laurent Poirel and R{\'e}my A Bonnin and Anne E Boulanger and Jacques Schrenzel and Martin Kaase and Patrice L. Nordmann},
  journal={Antimicrobial agents and chemotherapy},
  year={2012},
  volume={56 2},
  pages={1087-9}
}
A multidrug-resistant Acinetobacter baumannii isolate recovered from a patient hospitalized in Switzerland after a transfer from Serbia produced the NDM-1 carbapenemase. The bla(NDM-1) gene was part of a chromosomally located Tn125 composite transposon bracketed by two copies of the same insertion sequence, ISAba125. This transposon was also associated with the acquisition and expression of the bla(NDM-2) gene in an A. baumannii isolate in Germany. Tn125 appears to be the main vehicle for… CONTINUE READING
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