Tmem176B and Tmem176A are associated with the immature state of dendritic cells.

@article{Condamine2010Tmem176BAT,
  title={Tmem176B and Tmem176A are associated with the immature state of dendritic cells.},
  author={Thomas Condamine and Laetitia Le Texier and Duncan Howie and Am{\'e}lie Lavault and Marcelo Hill and Frank Halary and Steve Cobbold and Herman Waldmann and Maria-Cristina Cuturi and Elise Chiffoleau},
  journal={Journal of leukocyte biology},
  year={2010},
  volume={88 3},
  pages={
          507-15
        }
}
  • Thomas Condamine, Laetitia Le Texier, +7 authors Elise Chiffoleau
  • Published in Journal of leukocyte biology 2010
  • Biology, Medicine
  • DCs play a central role in the development of innate and adaptive immunity but also in the induction and maintenance of immune tolerance. Identification of factors that govern DC activation, their maturation state, and their capacity to induce proinflammatory or tolerogeneic responses therefore represents a crucial aim of research. We previously identified a new molecule, Tmem176B (which we named TORID initially), as highly expressed in a model of allograft tolerance in the rat. We showed that… CONTINUE READING

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