Tlr2 is critical for diet-induced metabolic syndrome in a murine model.

@article{Himes2010Tlr2IC,
  title={Tlr2 is critical for diet-induced metabolic syndrome in a murine model.},
  author={Ryan W Himes and Clifton Smith},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2010},
  volume={24 3},
  pages={731-9}
}
Obesity and its associated comorbidities, termed metabolic syndrome, are increasingly prevalent, and they pose a serious threat to the health of individuals and populations. Gene-environment interactions have been scrutinized since the kinetics of the increased prevalence of obesity would argue against a purely genetic etiology. Toll-like receptors (TLRs), widely expressed and highly conserved transmembrane receptors, are at the intersection of diet and metabolism, and may therefore be… CONTINUE READING