Tizanidine in the management of trigeminal neuralgia.

  title={Tizanidine in the management of trigeminal neuralgia.},
  author={Steinar T. Vilming and Torstein Lyberg and X. Lataste},
  journal={Cephalalgia : an international journal of headache},
  volume={6 3},
In a double-blind study the efficacy and tolerability of tizanidine was compared with those of carbamazepine in the management of trigeminal neuralgia. Six patients were allocated to treatment with tizanidine and six to carbamazepine. After individual titration the maximum daily doses were 18 mg and 900 mg, respectively. Among the efficacy factors used, the visual analog scale (VAS) and the overall efficacy as assessed by patients and investigator turned out to be the most appropriate. The… CONTINUE READING