Titrating steroids on exhaled nitric oxide in children with asthma: a randomized controlled trial.


RATIONALE Corticosteroids are the antiinflammatory treatment of choice in asthma. Treatment guidelines are mainly symptom-driven but symptoms are not closely related to airway inflammation. The fraction of nitric oxide in exhaled air (FENO) is a marker of airway inflammation in asthma. OBJECTIVE We evaluated whether titrating steroids on FENO improved… (More)


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