Title Critical role of TNF-alpha-TNFR 1 signaling in intracranialaneurysm formation

@inproceedings{Aoki2016TitleCR,
  title={Title Critical role of TNF-alpha-TNFR 1 signaling in intracranialaneurysm formation},
  author={Tomohiro Aoki and Miyuki Fukuda and Masaki Nishimura and Kazuhiko Nozaki and Shuh Narumiya},
  year={2016}
}
Background: Intracranial aneurysm (IA) is a socially important disease due to its high incidence in the general public and the severity of resultant subarachnoid hemorrhage that follows rupture. Despite the social importance of IA as a cause of subarachnoid hemorrhage, there is no medical treatment to prevent rupture, except for surgical procedures, because the mechanisms regulating IA formation are poorly understood. Therefore, these mechanisms should be elucidated to identify a therapeutic… CONTINUE READING