Title : Preclinical efficacy of the anti - hepatocyte growth factor antibody

Abstract

Purpose: Ficlatuzumab is a novel therapeutic agent targeting the hepatocyte growth factor (HGF)/c-MET pathway. We summarize extensive preclinical work using this agent in a mouse brain orthotopic model of glioblastoma. Experimental Design: Sequential experiments were done using 8to 9-week old nude mice injected with 3x10 U87 MG (glioblastoma) cells into the… (More)

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Cite this paper

@inproceedings{Mittra2013TitleP, title={Title : Preclinical efficacy of the anti - hepatocyte growth factor antibody}, author={Erik Mittra and Hua Fan-Minogue and Frank Lin and Jason Karamchandani and Venkataraman Sriram and May Htwe Han and Sanjiv S. Gambhir and Sanjiv Sam Gambhir and James H. Clark}, year={2013} }