Title : HIV-1 Infection of hematopoietic progenitor cells in vivo in humanized mice

Abstract

HIV infection has been associated with defective hematopoiesis since the earliest days of the HIV/AIDS epidemic. Generation of all hematopoietic lineages suffers in the face of infection. The mechanisms by which HIV impairs normal blood cell development remain unclear and direct infection of intermediate hematopoietic progenitors has not been established as… (More)

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